Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DLAT All Species: 25.76
Human Site: S98 Identified Species: 35.42
UniProt: P10515 Number Species: 16
    Phosphosite Substitution
    Charge Score: 0.06
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P10515 NP_001922.2 647 68997 S98 H Q K V P L P S L S P T M Q A
Chimpanzee Pan troglodytes XP_522180 647 68973 S98 H Q K V P L P S L S P T M Q A
Rhesus Macaque Macaca mulatta XP_001107013 647 68918 S98 H Q K V P L P S L S P T M Q A
Dog Lupus familis XP_546524 647 68802 S98 H Q K V P L P S L S P T M Q A
Cat Felis silvestris
Mouse Mus musculus Q8BMF4 642 67923 S97 H Q K V P L P S L S P T M Q A
Rat Rattus norvegicus P08461 632 67147 S89 H Q K V P L P S L S P T M Q A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509202 536 56600 S12 E R A N E C P S Q V E T D K A
Chicken Gallus gallus XP_417933 681 72018 A126 H Q K V A L P A L S P T M Q M
Frog Xenopus laevis NP_001082239 628 66845 T83 P L P A L S P T M Q M G T I A
Zebra Danio Brachydanio rerio NP_997832 652 69250 A99 H Q K V E L P A L S P T M Q M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_609118 512 54233
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19749 507 53448
Sea Urchin Strong. purpuratus XP_001190217 487 52117
Poplar Tree Populus trichocarpa XP_002303212 512 55370
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q5M729 539 58449 D16 N H S K K L K D V S T L L R R
Baker's Yeast Sacchar. cerevisiae P12695 482 51800
Red Bread Mold Neurospora crassa P20285 458 48601
Conservation
Percent
Protein Identity: 100 99.2 98.1 89.4 N.A. 85.6 85.1 N.A. 70.3 72 72.8 71.9 N.A. 42 N.A. 41.7 39.8
Protein Similarity: 100 99.2 98.6 92.8 N.A. 90.2 89.6 N.A. 74.5 78.4 82.6 78.9 N.A. 53.9 N.A. 55 54.1
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 26.6 80 13.3 80 N.A. 0 N.A. 0 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 86.6 26.6 86.6 N.A. 0 N.A. 0 0
Percent
Protein Identity: 36.3 N.A. N.A. 38.6 33.5 36.6
Protein Similarity: 50.2 N.A. N.A. 53 48.2 48.8
P-Site Identity: 0 N.A. N.A. 13.3 0 0
P-Site Similarity: 0 N.A. N.A. 40 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 6 6 6 0 0 12 0 0 0 0 0 0 48 % A
% Cys: 0 0 0 0 0 6 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 6 0 0 0 0 6 0 0 % D
% Glu: 6 0 0 0 12 0 0 0 0 0 6 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 6 0 0 0 % G
% His: 48 6 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 6 0 % I
% Lys: 0 0 48 6 6 0 6 0 0 0 0 0 0 6 0 % K
% Leu: 0 6 0 0 6 53 0 0 48 0 0 6 6 0 0 % L
% Met: 0 0 0 0 0 0 0 0 6 0 6 0 48 0 12 % M
% Asn: 6 0 0 6 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 6 0 6 0 36 0 59 0 0 0 48 0 0 0 0 % P
% Gln: 0 48 0 0 0 0 0 0 6 6 0 0 0 48 0 % Q
% Arg: 0 6 0 0 0 0 0 0 0 0 0 0 0 6 6 % R
% Ser: 0 0 6 0 0 6 0 42 0 53 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 6 0 0 6 53 6 0 0 % T
% Val: 0 0 0 48 0 0 0 0 6 6 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _